Immunity induced in rats vaccinated with toxoid prepared from heat-labile toxin produced by Pasteurella multocida serogroup D.

نویسندگان

  • J R Thurston
  • R B Rimler
  • M R Ackermann
  • N F Cheville
  • J M Sacks
چکیده

Rats were vaccinated with a toxoid (D-toxoid) prepared from purified heat-labile toxin (D-toxin) produced by Pasteurella multocida serogroup D. Vaccination of rats with D-toxoid prevented death and other effects of D-toxin (hepatic necrosis, development of elevated leukocyte counts, lymphopenia, neutrophilia, and elevated complement titers) that occurred in phosphate buffered saline (PBS)-vaccinated control rats.

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عنوان ژورنال:
  • Veterinary microbiology

دوره 27 2  شماره 

صفحات  -

تاریخ انتشار 1991